This randomized double-blind study evaluated the effectiveness of superpulsed low-level laser therapy (SLLLT) compared with ibuprofen and placebo in managing temporomandibular joint disorders (TMD) related to disc displacement without reduction or osteoarthritis. A total of 99 patients were divided into three groups: SLLLT (39 patients, 10 sessions), ibuprofen (30 patients, 800 mg twice daily for 10 days), and sham laser placebo (30 patients). Pain intensity (VAS) and mandibular function were assessed throughout treatment and follow-up. Results showed that SLLLT significantly reduced pain compared with both ibuprofen and placebo from day 5 onward (P=0.0001). Additionally, improvements in active and passive mouth opening and lateral motions were more evident in the SLLLT group after 1 month (P=0.0001). Overall, SLLLT demonstrated superior efficacy in pain relief and functional recovery, proving its effectiveness as a noninvasive therapy for TMD.

This systematic review evaluated 40 studies (in vitro and in vivo) to assess how lasers affect the whitening of natural teeth and dental restorative materials, compared to conventional bleaching. Diode lasers (808-980 nm) were used most often; about a quarter of these showed better whitening than standard methods. KTP, Er: YAG, and Er,Cr: YSGG lasers also demonstrated beneficial effects, though with more variability in efficacy and longer exposure in some cases. In contrast, argon and AsGaAl lasers were generally not more effective than conventional bleaching. Restorative materials, such as composites and ceramics, showed limited or no substantial whitening; composites in some studies even suffered adverse changes in surface properties and increased risk of future discoloration. The review concludes that laser-assisted bleaching can improve outcomes for natural teeth, but more research is needed, especially regarding safety and effects on restorative materials.

Recent advancements in dental diagnostics highlight laser fluorescence (LF) as a promising tool. This report explores the use of a 405 nm diode laser in treating biofilm-induced gingivitis and diagnosing restorations and caries in two patients (24-year-old male, 21-year-old female). In the first case, the laser improved visualization of plaque and calculus, aiding patient education and enabling precise mechanical debridement for better gingivitis treatment outcomes. In the second case, it detected defective composite fillings, supporting accurate diagnosis and patient communication for re-treatment. The 405 nm diode laser proves valuable for periodontal care and restorative dentistry.

This prospective, single-center study evaluated the safety and efficacy of 1940 nm endovenous laser ablation (EVLA) with a radial fiber over a 3-year follow-up. A total of 177 procedures were performed on incompetent great and small saphenous veins. The results showed significant reductions in vein diameter and complete disappearance of treated segments. Compared to historical data on 1470 nm EVLA, the 1940 nm laser demonstrated lower postoperative pain, fewer complications, and effective vein occlusion with less energy. Manual pullback and individualized dosimetry (40–60 J/cm) contributed to favorable outcomes. While the study was non-randomized and limited by COVID-19, findings support the use of 1940 nm EVLA as a safe, efficient option for treating truncal vein incompetence. Further randomized studies are recommended.

This pilot study investigates the combined effects of conventional podiatric intervention and phototherapy on chronic lower-limb ulcers in patients with type 2 diabetes mellitus. The authors recruited seven patients with a total of 15 ulcers and assigned them to three groups receiving either standard care with placebo phototherapy, phototherapy applied directly to ulcers, or phototherapy to both ulcers and regional lymph nodes.

Results demonstrated enhanced healing outcomes in groups receiving phototherapy, with 40% of treated ulcers completely resolving within 8 weeks and no adverse effects reported. The group receiving phototherapy only on the ulcers showed the most favorable healing rate, while additional irradiation of lymph nodes did not significantly improve outcomes.

The study explores the clinical application of a 1470 nm laser combined with a fractional (Frax) handpiece for non-invasive facial rejuvenation. A total of 30 female patients with moderate facial wrinkles and skin laxity underwent treatment sessions spaced 4–6 weeks apart. The Frax handpiece utilizes a microneedle-like array to deliver subdermal laser energy in a fractional pattern, targeting collagen-rich dermal tissue while sparing the epidermis. Evaluations showed statistically significant improvements in skin tightening and wrinkle reduction, with minimal adverse effects such as transient erythema and edema. Pain scores were low, and most patients reported high satisfaction with the aesthetic outcomes. Histological analysis confirmed new collagen and elastin formation post-treatment. The findings suggest that the 1470 nm Frax system is a safe, effective, and patient-friendly modality for facial skin rejuvenation, offering advantages such as minimal downtime, precision targeting, and suitability for diverse skin types.