Industry Resources - a-PDT

Can Antimicrobial Photodynamic Therapy (aPDT)Enhance the Endodontic Treatment?

Can Antimicrobial Photodynamic Therapy (aPDT)Enhance the Endodontic Treatment?

The study aimed to evaluate scientific literature on using different photosensitizers (PSs) for bacterial reduction in root canal treatment, particularly against Enterococcus faecalis. Databases such as PubMed, Scopus, and Google Scholar were searched with relevant keywords from 2000 to 2015. It was concluded that antimicrobial photodynamic therapy (aPDT) should be used alongside conventional mechanical debridement and irrigants for effective bacterial elimination. However, the success rate of aPDT depends on factors like the type of PS, laser output power, irradiation time, pre-irradiation time, and type of tips used.

 


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Clinical applications of antimicrobial photodynamic therapy in dentistry

Clinical applications of antimicrobial photodynamic therapy in dentistry

Antimicrobial photodynamic therapy (aPDT) is emerging as a promising non-invasive treatment for oral infections. It has been effective against bacteria, fungi, and viruses, including pathogens like Streptococcus mutans, Porphyromonas gingivalis, Candida albicans, and Enterococcus faecalis. Advances in natural, nano-based, and targeted photosensitizers have enhanced its efficacy. Clinical studies, crucial for evidence-based applications, have shown aPDT to be effective in reducing pathogenic bacterial loads in periodontal, peri-implant, and persistent endodontic infections. However, more randomized clinical trials are needed to determine optimal protocols and parameters. Further high-quality trials with specific photosensitizers and irradiation parameters are essential for establishing effective clinical practices.


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